- Adept Scientific
 - Technical software for scientists and engineers - BAC Computer Software
- Products include a fraction and mortgage calculator, algebra cheat, and a board game. Also offers WHATSGone, which provides an analysis of disc drives and shows how the space is used.
- CenterSpace Software
- Offers .NET numerical and statistical libraries including matrix, vector, regression, ANOVA, and C# interfaces to the BLAS and LAPACK. CenterSpace component libraries offer a simple royalty-free licensing model.
- Chartwell-Yorke
- Sells mathematics software and books.
- CPLEX Optimization, Inc.
- Is a leading provider of large-scale mathematical programming software and services
- Data Description, Inc.
- Developer of statistics and statistics training software for Macintosh, Windows 95, and Windows NT computers.
- Datatrend Software
- Digitize graphs and charts. Also contains angle and distance measurement functions, and real-time data display.
- Eldecsoft Co.
- Offers software that uses modified genetic algorithm technology to quickly solve complex optimisation problems in finance, distribution, scheduling, resource allocation, manufacturing, budgeting, engineering, and more.
- Fast Mathematical Algorithms & Hardware
- Developed for industrial and technological environments.
- Frontline Systems Inc
- Developers of the Solver in Microsoft Excel.
- GAMS Development Corporation
- Modelling tools for mathematical optimisation.
- Harmonic Software Inc.
- O-Matrix is a visual data analysis environment with the performance capabilities of a compiled language and the ease of use of an integrated environment.
- Insightful Corporation (2)
- Ketrom Management Science
- Specialises in the consulting, design, development and application of mathematical software for management science uses.
- LINDO Systems
- Supplier of software for linear, integer, and nonlinear programming.
- MacKichan Software
- Producers of Scientific WorkPlace, Scientific Word, and Scientific Notebook.
- MAPLE
- Maplesoft is a developer of interactive mathematical software.
- Math-Tech
- Situated in Denmark and is specialised in developing software in the areas of medicotechnics and parallel computing.
- MathCore AB
- Develops engineering tools for technical computing such as modelling, simulation, verification and code generation.
- MathTools
- Makers of MATCOM and Matlab to C++ compiler which creates MEX files and standalone C++ applications.
- MathWorks (5)
- Math_Vally
- In French.
- Maximal Software, Inc.
- Developer of the MPL modelling system and optimax 2000 component library for building mathematical optimisation models.
- Minitab, Inc.
- Is a producer and manufacturer of statistical software; widely used in academia and total quality management
- Multipath Corporation
- Producers of Fast Matrix Solver, for performing matrix algebra operations.
- Numerical Objects AS
- Developing and marketing object-oriented software solutions for technical and scientific computing.
- NumeriX LLC
- Making real-time derivatives pricing and risk management a reality by providing enhancements to complex financial computations.
- Optimal Designs Enterprise Software
- Math shareware software for engineers and scientists. Optimal Designs Enterprise offers CurvFit for fitting hard multi-peaked data, ODEcalc calculator for solving differential equations, Rainbow for finding spectral content in data, and other titles.
- Optimset
- Consulting and software development company specialising in large-scale multicriteria combinatorial optimisation.
- Perfectly Scientific, Inc.
- Scientific algorithms: fractals, compression, wavelets, general transforms, large numbers, image processing, FFT, Monte Carlo, convolution, and more.
- Quantitative Micro Software
- Develops forecasting and econometric analysis software.
- Saltire Software
- Geometry-centred products based on constraints. AlgebraicGeometer allows you to output a symbolic form of your geometry to Maple or Mathematica.
- Shazam Econometrics Software
- Or econometricians, statisticians, engineers, sociometricians, psychometricians, and others who use statistical techniques.
- Soft Warehouse, Inc.
- Developers of Derive, a mathematical assistant for calculus and linear algebra, and muLisp90, a LISP programming environment.
- Statistical Solutions, Ltd.
- Distributes and supports a range of scientific and technical statistical software applications.
- Steven M. Christensen and Associates
- Offers scientific computing consulting and programme development for corporations and universities.
- TSP International
- Makers of TSP, a complete econometric software package.
- Universal Technical Systems, Inc
- Publishes TK Solver, equation solving for engineering and math modelling. Applications include plastic gear design, stress, mechanical, thermal, dynamics, and machine design.
- Visual Numerics, Inc.
- Provider of Web-enabled visualisation, computation, analysis and network software solutions. Products include: PV-WAVE, JWAVE, IMSL, JNL, SmartTable, DNFL and FORGExplorer.
- Wolfram Research, Inc. (7)
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