- MIDAC Corporation
- Irvine - Spectrometer manufacturer for scientific and industrial materials science, chemical, and environmental applications. - Cartesian Technologies, Inc.
- Irvine - Manufactures equipment for DNA microarrays, high throughput screening (HTS), genomics, drug discovery, and combinatorial chemistry. - Reynard Corporation
- San Clemente - Global supplier of optical components to the commercial and military aerospace markets. The site includes R&D capabilities, coating services, stock products, site maps, and contact information.
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